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1.1.99.24: hydroxyacid-oxoacid transhydrogenase

This is an abbreviated version!
For detailed information about hydroxyacid-oxoacid transhydrogenase, go to the full flat file.

Word Map on EC 1.1.99.24

Reaction

(S)-3-hydroxybutanoate
+
2-oxoglutarate
=
acetoacetate
+
(R)-2-hydroxyglutarate

Synonyms

ADHFE1, alcohol dehydrogenase iron containing 1, HOT, hydroxyacid-oxoacid transhydrogenase, iron-dependent alcohol dehydrogenase ADHFe1, transhydrogenase, hydroxy acid-oxo acid

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.24 hydroxyacid-oxoacid transhydrogenase

Systematic Name

Systematic Name on EC 1.1.99.24 - hydroxyacid-oxoacid transhydrogenase

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SYSTEMATIC NAME
IUBMB Comments
(S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase
4-Hydroxybutanoate and (R)-2-hydroxyglutarate can also act as donors; 4-oxobutanoate can also act as acceptor.