Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.1.99.18: cellobiose dehydrogenase (acceptor)

This is an abbreviated version!
For detailed information about cellobiose dehydrogenase (acceptor), go to the full flat file.

Word Map on EC 1.1.99.18

Reaction

cellobiose
+
acceptor
=
cellobiono-1,5-lactone
+
reduced acceptor

Synonyms

cbdA, CBO, CBOR, Cdh, CDH IIA, CDH IIB, cdh-1, CDH1, Cdh2, CDHIIA, cellobiose (acceptor) 1-oxidoreductase, cellobiose dehydrogenase, cellobiose dehydrogenase IIA, cellobiose oxidase, cellobiose oxidoreductase, cellobiose [acceptor] 1-oxidoreductase, Cellobiose-quinone oxidoreductase, cellobiose:(acceptor) 1-oxidoreductase, cellobiose:quinone oxidoreductase, cellobiose:[acceptor] 1-oxidoreductase, DCHsr, dehydrogenase, cellobiose, EC 1.1.3.25, EC 1.1.5.1, MtCDH, oxidase, cellobiose, Thite_59724, TpCDH, TvCDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.18 cellobiose dehydrogenase (acceptor)

General Information

General Information on EC 1.1.99.18 - cellobiose dehydrogenase (acceptor)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
a phylogenetic tree using basidiomycetes and ascomycetes CDH sequences shows that the CDH from Termitomyces clypeatus, which is classified as a basidiomycetes fungus, is clustered with the ascomycetes group
malfunction
-
the three CDH genes of Podospora anserina are inactivated, resulting in single and multiple CDH mutants. Almost no difference is detected in growth and fertility of the mutants on various lignocellulose sources, except on crystalline cellulose, on which a 2fold decrease in fertility of the mutants lacking Podospora anserina CDH1 (PaCDH1) and PaCDH2 is observed. A striking difference between wild-type and mutant secretomes is observed. The secretome of the mutant lacking all CDHs contains five beta-glucosidases, whereas the wild type had only one. Podospora anserina seems to compensate for the lack of CDH with secretion of beta-glucosidases
metabolism
physiological function