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1.1.5.3: glycerol-3-phosphate dehydrogenase

This is an abbreviated version!
For detailed information about glycerol-3-phosphate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.5.3

Reaction

sn-glycerol 3-phosphate
+
a quinone
=
glycerone phosphate
+
a quinol

Synonyms

DsFAD-GPDH, EC 1.1.2.1, EC 1.1.99.5, FAD-dependent glycerol-3-phosphate dehydrogenase, FAD-G3PDH, FAD-glycerol phosphate dehydrogenase, FAD-GPDH, FAD-linked glycerol-3-phosphate dehydrogenase, flavin adenine dinucleotide-dependent glycerol-3-phosphate dehydrogenase, flavin-linked glycerol-3-phosphate ubiquinone oxidoreductase, flavoprotein-dependent glycerol-3-phosphate dehydrogenase, G3PD, GDP, GLPD, GlpO, glycerol-3-phosphate dehydrogenase, glycerol-3-phosphate dehydrogenase 1, glycerol-3-phosphate dehydrogenase 2, glycerol-3-phosphate oxidoreductase, glycerophosphate dehydrogenase, GmGPDH12, GPD1, GPD2, GPDH, mGPDH, mitochondrial glycerol-3-phosphate dehydrogenase, mitochondrial sn-glycerol 3-phosphate dehydrogenase, mtG3PDH, putG3PDH, SDP6, sn-glycerol 3-phosphate dehydrogenase, sn-glycerol-3-phosphate dehydrogenase, ZmGPDH6

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.5 With a quinone or similar compound as acceptor
                1.1.5.3 glycerol-3-phosphate dehydrogenase

IC50 Value

IC50 Value on EC 1.1.5.3 - glycerol-3-phosphate dehydrogenase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.05
4-[3-(1H-benzimidazol-2-yl)anilino]-4-oxobutanoic acid
Mus musculus
pH not specified in the publication, 37°C
0.015
4-[4-(1,3-benzothiazol-2-yl)anilino]-4-oxobutanoic acid
Mus musculus
pH not specified in the publication, 37°C
0.02
4-[4-(1,3-benzoxazol-2-yl)anilino]-4-oxobutanoic acid
Mus musculus
pH not specified in the publication, 37°C
0.0063 - 0.008
4-[4-(1H-benzimidazol-2-yl)anilino]-4-oxobutanoic acid
Mus musculus
pH not specified in the publication, 37°C
0.0007 - 0.001
4-[4-(1H-naphtho[2,3-d]imidazol-2-yl)anilino]-4-oxobutanoic acid
Mus musculus
pH not specified in the publication, 37°C
0.005
4-[4-(5-methyl-1H-benzimidazol-2-yl)anilino]-4-oxobutanoic acid
Mus musculus
pH not specified in the publication, 37°C
0.003
4-[4-[5-(cyclohexa-2,4-diene-1-carbonyl)-1H-benzimidazol-2-yl]anilino]-4-oxobutanoic acid
Mus musculus
pH not specified in the publication, 37°C
0.0006
6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol
Giardia intestinalis
-
at pH 7.5 and 25°C
0.0019
metronidazole
Giardia intestinalis
-
at pH 7.5 and 25°C
0.08
N-[4-(5,6-dihydro-1H-benzimidazol-2-yl)phenyl]furan-2-carboxamide
Mus musculus
pH not specified in the publication, 37°C