1.1.5.3: glycerol-3-phosphate dehydrogenase

This is an abbreviated version!
For detailed information about glycerol-3-phosphate dehydrogenase, go to the full flat file.

Reaction

Synonyms

DsFAD-GPDH, EC 1.1.2.1, EC 1.1.99.5, FAD-dependent glycerol-3-phosphate dehydrogenase, FAD-G3PDH, FAD-glycerol phosphate dehydrogenase, FAD-GPDH, FAD-linked glycerol-3-phosphate dehydrogenase, flavin adenine dinucleotide-dependent glycerol-3-phosphate dehydrogenase, flavin-linked glycerol-3-phosphate ubiquinone oxidoreductase, flavoprotein-dependent glycerol-3-phosphate dehydrogenase, G3PD, GDP, GLPD, GlpO, glycerol-3-phosphate dehydrogenase, glycerol-3-phosphate dehydrogenase 1, glycerol-3-phosphate dehydrogenase 2, glycerol-3-phosphate oxidoreductase, glycerophosphate dehydrogenase, GmGPDH12, GPD1, GPD2, GPDH, mGPDH, mitochondrial glycerol-3-phosphate dehydrogenase, mitochondrial sn-glycerol 3-phosphate dehydrogenase, mtG3PDH, putG3PDH, SDP6, sn-glycerol 3-phosphate dehydrogenase, sn-glycerol-3-phosphate dehydrogenase, ZmGPDH6

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.5 With a quinone or similar compound as acceptor

                1.1.5.3 glycerol-3-phosphate dehydrogenase

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Results	in table
10	Activating Compound
32033	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
31	Cofactor
3	Crystallization (Commentary)
290	Disease/ Diagnostics
2	Expression
17	General Information
2	General Stability
10	IC50 Value
111	Inhibitors
4	Ki Value [mM]
27	KM Value [mM]
39	Localization
21	Metals/Ions
16	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
217	Organism
12	Pathway
4	pH Optimum
1	pH Stability
1	pI Value
7	Posttranslational Modification
13	Purification (Commentary)
2	Reaction
47	Reference
42	Source Tissue
5	Specific Activity [micromol/min/mg]
4	Storage Stability
98	Substrates and Products (Substrate)
12	Subunits
72	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 1.1.5.3 - glycerol-3-phosphate dehydrogenase

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ACTIVATING COMPOUND

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

Bathocuproine

Cyberlindnera jadinii

-

slight activation

287805

cardiolipin

Rattus norvegicus

-

when functioning with hydrophobic electron acceptor essential in both leaflets of the membrane

287828

chloroform

Cyberlindnera jadinii

-

slight activation

287805

cytochrome c

Rattus norvegicus

-

role of cyt c in activation of glycerol-3-phosphate and succinate oxidation in frozenthawed mitochondria

723350

detergent

2 entries

-

FAD

Escherichia coli

-

stimulates the reaction with phenazine methosulfate and methylene blue. 20% increase in activity of the reaction with phenazine methosulfate with a half-maximal concentration of 200 nM

287817

FMN

Escherichia coli

-

stimulates the reaction with phenazine methosulfate. 6fold increase in activity with a half-maximal concentration of 0.13 mM

287817

Phospholipid

Escherichia coli

-

detergent-depleted enzyme requires exogenous phospholipid or nondenaturing detergent for activity

287818

sodium oleate

Rattus norvegicus

-

activates

287829

detergent

Escherichia coli

-

detergent-depleted enzyme requires exogenous phospholipid or nondenaturing detergent for activity

287818

-

detergent

Vibrio alginolyticus

-

required for maximal activity

287807

-