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1.1.5.10: D-2-hydroxyacid dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about D-2-hydroxyacid dehydrogenase (quinone), go to the full flat file.

Word Map on EC 1.1.5.10

Reaction

(R)-2-hydroxyacid
+
a quinone
=
2-oxoacid
+
a quinol

Synonyms

(R)-2-hydroxy acid dehydrogenase, (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase, D-lactate dehydrogenase, DLD, Fe-S D-iLDH, lldE, NAD-independent D-lactate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.5 With a quinone or similar compound as acceptor
                1.1.5.10 D-2-hydroxyacid dehydrogenase (quinone)

Systematic Name

Systematic Name on EC 1.1.5.10 - D-2-hydroxyacid dehydrogenase (quinone)

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SYSTEMATIC NAME
IUBMB Comments
(R)-2-hydroxyacid:quinone oxidoreductase
The enzyme from mammalian kidney contains one mole of FAD per mole of enzyme.(R)-lactate, (R)-malate and meso-tartrate are good substrates. Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD+ and NADP+ are not acceptors.