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1.1.5.10: D-2-hydroxyacid dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about D-2-hydroxyacid dehydrogenase (quinone), go to the full flat file.

Word Map on EC 1.1.5.10

Reaction

(R)-2-hydroxyacid
+
a quinone
=
2-oxoacid
+
a quinol

Synonyms

(R)-2-hydroxy acid dehydrogenase, (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase, D-lactate dehydrogenase, DLD, Fe-S D-iLDH, lldE, NAD-independent D-lactate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.5 With a quinone or similar compound as acceptor
                1.1.5.10 D-2-hydroxyacid dehydrogenase (quinone)

Inhibitors

Inhibitors on EC 1.1.5.10 - D-2-hydroxyacid dehydrogenase (quinone)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
antimycin A
inhibits electron transfer from quinone to cytochrome c
Ba2+
5 mM, partial inhibition of activity
Ca2+
5 mM, partial inhibition of activity
Cd2+
5 mM, complete inhibition of activity
Co2+
5 mM, complete inhibition of activity
Cu2+
5 mM, complete inhibition of activity
EDTA
5 mM, partial inhibition of activity
Fe2+
5 mM, complete inhibition of activity
Mg2+
5 mM, partial inhibition of activity
Mn2+
5 mM, complete inhibition of activity
NaN3
inhibits electron transfer from cytochrome c to molecular oxygen
Ni2+
5 mM, partial inhibition of activity
oxalate
oxaloacetate
-
-
Zn2+
5 mM, complete inhibition of activity