1.1.2.B2: quinoprotein methanol dehydrogenase (cytochrome c551i)

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For detailed information about quinoprotein methanol dehydrogenase (cytochrome c551i), go to the full flat file.

Reaction

Synonyms

MEDH, MEDH-PD, methanol dehydrogenase, quinoprotein methanol dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.2 With a cytochrome as acceptor

                1.1.2.B2 quinoprotein methanol dehydrogenase (cytochrome c551i)

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Results	in table
2	Activating Compound
1	AA Sequence
3	Cofactor
1	Crystallization (Commentary)
5	Inhibitors
2	Ki Value [mM]
6	KM Value [mM]
1	Localization
2	Metals/Ions
2	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
3	Organism
2	pH Optimum
1	pH Range
1	pH Stability
1	Purification (Commentary)
1	Reaction
3	Reference
1	Source Tissue
2	Specific Activity [micromol/min/mg]
10	Substrates and Products (Substrate)
1	Subunits
5	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 1.1.2.B2 - quinoprotein methanol dehydrogenase (cytochrome c551i)

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

cyanide

Paracoccus denitrificans

P12293

suppresses the peculiar endogenous reaction of methanol dehydrogenase, and is also both an activator of substrate-dependent activity and a competitive inhibitor with respect to methanol, the two activities correspond to two distinct binding sites for cyanide, overview

685051

EDTA

Paracoccus denitrificans

-

decreases enzyme thermal stability

686814

KCN

Paracoccus denitrificans

-

-

686814

N,N,N',N'-tetramethyl-4-phenylenediamine

Paracoccus denitrificans

P12293

i.e. Wurster's blue

685051

phenazine ethosulfate

Paracoccus denitrificans

P12293

the articficial cofactor exhibits strong substrate inhibition

685051