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1.1.1.B3: (S)-specific secondary alcohol dehydrogenase

This is an abbreviated version!
For detailed information about (S)-specific secondary alcohol dehydrogenase, go to the full flat file.

Reaction

(S)-R-CHOH-R'
+
NAD+
=
R-CO-R'
+
NADH
+
H+

Synonyms

(S)-1-phenylethanol dehydrogenase, (S)-1-phenylethanolsynthase, acetophenone reductase, ADH, ADH-A, ADH1, ADH2, ADHTt, APRD, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CRII, More, NAD+-dependent (S)-stereospecific alcohol dehydrogenase, NAD+-dependent ADH, PED, S-ADH, SADH, Scr2, SDR, short chain dehydrogenase, short-chain NAD(H)-dependent alcohol dehydrogenase, SOU1, SPES, TtADH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B3 (S)-specific secondary alcohol dehydrogenase

pH Range

pH Range on EC 1.1.1.B3 - (S)-specific secondary alcohol dehydrogenase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5.5 - 6.5
Nocardia fusca AKU 2123
-
reduction reaction
5.5 - 7
more than 80% of maximum activity within
6 - 7.7
-
reduction reaction, high activity
6.5 - 7
-
more than 80% of maximum activity
8.5 - 9.5
Nocardia fusca AKU 2123
-
oxidation reaction
9 - 10
-
oxidation reaction, high activity