1.1.1.387: L-serine 3-dehydrogenase (NAD+)
This is an abbreviated version!
For detailed information about L-serine 3-dehydrogenase (NAD+), go to the full flat file.
Reaction
Synonyms
L-SerDH, L-serine 3-dehydrogenase, L-serine dehydrogenase, NAD+-dependent L-serine dehydrogenase, PA0743
ECTree
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Cofactor
Cofactor on EC 1.1.1.387 - L-serine 3-dehydrogenase (NAD+)
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additional information
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both NAD+ and NADP+ are capable of serving as cofactors for the enzyme, but the reaction rate with NADP+ is 7.9% of that observed with NAD+ with L-serine as substrate. Deamido-NAD+ is not able to serve as cofactor. Cofactor binding mechanism, overview
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NAD+
the enzyme can also use NADP+ as a cofactor for the oxidation of L-serine, but this activity is significantly lower than that with NAD+ (46%)
NADP+
the enzyme can also use NADP+ as a cofactor for the oxidation of L-serine, but this activity is significantly lower than that with NAD+ (46%)