Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.1.1.38: malate dehydrogenase (oxaloacetate-decarboxylating)

This is an abbreviated version!
For detailed information about malate dehydrogenase (oxaloacetate-decarboxylating), go to the full flat file.

Word Map on EC 1.1.1.38

Reaction

(S)-malate
+
NAD+
=
pyruvate
 +
CO2
 +
NADH
 +
H+

Synonyms

m-NAD(P)-ME, maeA, malic enzyme, malic enzyme 2, ME2, MHD, mitochondrial malic enzyme ME2, mitochondrial NAD(P) malic enzyme, mitochondrial NAD(P) malic enzyme ME2, mitochondrial NAD(P)+-dependent malic enzyme, mitochondrial NAD-malic enzyme, NAD+-dependent malic enzyme, NAD-dependent ME, NAD-malic enzyme, NAD-ME, NAD-specific malic enzyme, NADH-dependent malic enzyme, pyruvic-malic carboxylase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)

General Information

General Information on EC 1.1.1.38 - malate dehydrogenase (oxaloacetate-decarboxylating)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
metabolism
isoform Me2 funnels glucose carbons into malate-aspartate shuttle to sustain glycolysis
physiological function
the mitochondrial malic enzyme isoform Me2 functionally couples the mitochondria with aerobic glycolysis in osteoblasts
additional information