1.1.1.375: L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about L-2-hydroxycarboxylate dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

Synonyms

lactate/malate dehydrogenase, LDH-like L-MalDH, MdhII, MJ0409, MJ0490

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

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Results	in table
1	Activating Compound
6	AA Sequence
2	Cloned(Commentary)
13	Cofactor
3	Crystallization (Commentary)
1	Inhibitors
13	KM Value [mM]
5	Metals/Ions
2	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
21	Organism
1	Oxidation Stability
2	Pathway
4	pH Optimum
1	pH Range
4	Purification (Commentary)
1	Reaction
9	Reference
34	Substrates and Products (Substrate)
5	Subunits
16	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Stability [°C]

Sequence

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Sequence on EC 1.1.1.375 - L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

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UNIPROT

ENTRY NAME

ORGANISM

NO. OF AA

NO. OF TRANSM. HELICES

MOLECULAR WEIGHT[Da]

SOURCE

SEQUENCE

LOCALIZATION PREDICTIONThe reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).

Q60176 pBLAST

MDH_METJA

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

313

0

34609

Swiss-Prot

Show Sequence

-

A0A5E4LV62 pBLAST

A0A5E4LV62_9ARCH

uncultured archaeon

269

0

29448

TrEMBL

Show Sequence

-

A0A8D6PV36 pBLAST

A0A8D6PV36_9EURY

Methanocaldococcus sp. SG7

313

0

34337

TrEMBL

Show Sequence

-

A0A5E4HJM0 pBLAST

A0A5E4HJM0_9ARCH

uncultured archaeon

302

0

32759

TrEMBL

Show Sequence

-

A0A8D6SXF4 pBLAST

A0A8D6SXF4_9EURY

Methanocaldococcus sp. SG1

313

0

34337

TrEMBL

Show Sequence

-

O08349 pBLAST

MDH_ARCFU

Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)

294

0

31874

Swiss-Prot

Show Sequence

-

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