1.1.1.359: aldose 1-dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about aldose 1-dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

Synonyms

gdh-1, glucose dehydrogenase, SsGDH, SSO3003

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]

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Results	in table
3	AA Sequence
5	Cloned(Commentary)
9	Cofactor
2	Crystallization (Commentary)
1	General Information
1	General Stability
11	Inhibitors
29	kcat/KM [mM/s]
1	Ki Value [mM]
48	KM Value [mM]
6	Metals/Ions
10	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
5	Organic Solvent Stability
9	Organism
11	Pathway
8	pH Optimum
1	pH Stability
2	Protein Variants
6	Purification (Commentary)
1	Reaction
9	Reference
2	Source Tissue
3	Specific Activity [micromol/min/mg]
2	Storage Stability
44	Substrates and Products (Substrate)
4	Subunits
4	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
3	Temperature Stability [°C]
29	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.1.1.359 - aldose 1-dehydrogenase [NAD(P)+]

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an aldopyranose:NAD(P)+ 1-oxidoreductase

The enzyme from the archaeon Sulfolobus solfataricus shows broad specificity towards aldoses (D-glucose, D-galactose, D-xylose, L-arabinose, 6-deoxy-D-glucose, D-fucose) and can utilize NAD+ and NADP+ with similar catalytic efficiency. It is involved in aldose catabolism via the branched variant of the Entner-Doudoroff pathway.