1.1.1.354: farnesol dehydrogenase (NAD+)
This is an abbreviated version!
For detailed information about farnesol dehydrogenase (NAD+), go to the full flat file.
Word Map on EC 1.1.1.354
Reaction
Synonyms
farnesol dehydrogenase, GeDH, NAD+-farnesol dehydrogenase
ECTree
1.1.1.354 farnesol dehydrogenase (NAD+)Advanced search results
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Substrates Products on EC 1.1.1.354 - farnesol dehydrogenase (NAD+)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
3-methyl-2-buten-1-ol + NAD+
3-methyl-2-butenal + NADH + H+
4.3% of the activity compared to geraniol
-
-
?
citronellol + NAD+
?
4.3% of the activity compared to geraniol
-
-
?
additional information
?
-
straight-chain alcohols such as 1-octanol, 2-buten-1-ol, 1-butanol and ethanol serve as poor substrates
-
-
?
(2E,6E)-farnesol + NAD+
(2E,6E)-farnesal + NADH + H+
highest affinity for the active site of the FLDH enzyme, FLDH-encoded enzyme does not exhibit appreciable farnesal reductase activity
-
-
ir
(2E,6E)-farnesol + NAD+
(2E,6E)-farnesal + NADH + H+
key enzyme in biosynthesis of the alarm pheromone neral
-
-
?
(2E,6E)-farnesol + NAD+
(2E,6E)-farnesal + NADH + H+
50% of the activity compared to geraniol
-
-
?
geraniol + NAD+
geranial + NADH + H+
nerol, the geometrical isomer of geraniol is inactive. The enzyme cannot use NADP+ as cofactor
-
-
?
