1.1.1.351: phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
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For detailed information about phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating], go to the full flat file.
Reaction
Synonyms
6-phospho-D-gluconate dehydrogenase (decarboxylating), 6-phospho-D-gluconate:NADP+ 2-oxidoreductase, 6-phosphogluconate dehydrogenase, 6-phosphogluconate dehydrogenase (NADP+/NAD+), 6PGDH, gnd
ECTree
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Systematic Name
Systematic Name on EC 1.1.1.351 - phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
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6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase (decarboxylating)
The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce reducing power and pentose for biosynthetic reactions. Unlike EC 1.1.1.44, phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating), it is not specific for NADP+ and can accept both cofactors with similar efficiency. cf. EC 1.1.1.343, phosphogluconate dehydrogenase [NAD+-dependent, decarboxylating].