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1.1.1.303: diacetyl reductase [(R)-acetoin forming]

This is an abbreviated version!
For detailed information about diacetyl reductase [(R)-acetoin forming], go to the full flat file.

Reaction

(R)-acetoin
+
NAD+
=
diacetyl
+
NADH
+
H+

Synonyms

(R,R)-BDH, (R,R)-butane-2,3-diol dehydrogenase, (R,R)-butanediol dehydrogenase/diacetyl reductase, acetoin/diacetyl reductase, BdhA, DAR, dudA, EC 1.1.1.5, gutB, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.303 diacetyl reductase [(R)-acetoin forming]

Systematic Name

Systematic Name on EC 1.1.1.303 - diacetyl reductase [(R)-acetoin forming]

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SYSTEMATIC NAME
IUBMB Comments
(R)-acetoin:NAD+ oxidoreductase
The reaction is catalysed in the reverse direction. This activity is usually associated with butanediol dehydrogenase activity (EC 1.1.1.4 or EC 1.1.1.76). While the butanediol dehydrogenase activity is reversible, diacetyl reductase activity is irreversible. This enzyme has been reported in the yeast Saccharomyces cerevisiae [1,2]. Different from EC 1.1.1.304, diacetyl reductase [(S)-acetoin forming].