1.1.1.3: homoserine dehydrogenase

This is an abbreviated version!
For detailed information about homoserine dehydrogenase, go to the full flat file.

Reaction

Synonyms

AK-HDH, AK-HSD-1, AK-HSDH, AK-HseDH, aspartate kinase-homoserine dehydrogenase, aspartokinase-homoserine dehydrogenase I, bifunctional aspartate kinase-homoserine dehydrogenase, BsHSD, HDH, hom, hom-1, Hom6, homoserine dehydrogenase 1, homoserine dehydrogenase 2, HSD, HSDH, HseDH, More, orf19.2951, PbHSD, SACOL1362, StHSD, thrA, TM_0547, TTHA0489, TtHSD

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.3 homoserine dehydrogenase

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Results	in table
3	Activating Compound
46611	AA Sequence
13	Application
1	CAS Registry Number
20	Cloned(Commentary)
72	Cofactor
8	Crystallization (Commentary)
4	Expression
67	General Information
4	IC50 Value
111	Inhibitors
35	kcat/KM [mM/s]
7	Ki Value [mM]
88	KM Value [mM]
10	Localization
26	Metals/Ions
33	Molecular Weight [Da]
61	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
92	Organism
9	Pathway
50	PDB ID
16	pH Optimum
3	pH Range
2	pH Stability
2	Posttranslational Modification
54	Protein Variants
28	Purification (Commentary)
13	Reaction
3	Reaction Type
87	Reference
1	Renatured (Commentary)
16	Source Tissue
15	Specific Activity [micromol/min/mg]
4	Storage Stability
122	Substrates and Products (Substrate)
34	Subunits
101	Synonyms
1	Systematic Name
18	Temperature Optimum [°C]
3	Temperature Range [°C]
9	Temperature Stability [°C]
25	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 1.1.1.3 - homoserine dehydrogenase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C, 0.05 M potassium phosphate buffer, pH 7.5, 1.0 mM EDTA, 2.0 mM dithioerythritol, 5.0 mM L-threonine, 20% v/v glycerol, at least 2 years

Zea mays

-

246384

-20°C, 30 mM potassium phosphate buffer, pH 7.5, 50% v/v glycerol, threonine resistant isozyme at least 2 months stable, threonine sensitive isozyme at least 4 months stable

Zea mays

-

246385

-25°C, 50 mM potassium phosphate buffer, pH 7.2, 15% v/v glycerol, 1 mM EDTA, 1 mM threonine, 14 mM 2-mercaptoethanol

Pisum sativum

-

246391

-80°C, purified recombinant soluble enzyme, at 3 mg/ml, stable

Arabidopsis thaliana

O81852

642340