1.1.1.298: 3-hydroxypropionate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about 3-hydroxypropionate dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

3-HIBADH, 3-hydroxyisobutyrate dehydrogenase, 3-hydroxypropionate dehydrogenase, bi-functional malonyl-CoA reductase, malonate semialdehyde reductase, malonate semialdehyde reductase (NADPH), malonic semialdehyde reductase, malonyl-CoA reductase, MCR, More, MSAR, Msed_1993

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)

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Results	in table
2229	AA Sequence
3	Application
1	CAS Registry Number
8	Cloned(Commentary)
24	Cofactor
1	Crystallization (Commentary)
2	Expression
20	General Information
1	General Stability
4	Inhibitors
3	kcat/KM [mM/s]
11	KM Value [mM]
8	Metals/Ions
6	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
42	Organism
10	Pathway
6	pH Optimum
5	pH Range
9	Protein Variants
5	Purification (Commentary)
1	Reaction
20	Reference
3	Source Tissue
7	Specific Activity [micromol/min/mg]
1	Storage Stability
39	Substrates and Products (Substrate)
12	Subunits
40	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
4	Temperature Range [°C]
6	Temperature Stability [°C]
5	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 1.1.1.298 - 3-hydroxypropionate dehydrogenase (NADP+)

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.002

Chloroflexus aurantiacus

-

substrate 3-hydroxypropionate, pH 9.0, 45°C

288061

0.04

Chloroflexus aurantiacus

-

substrate malonate-semialdehyde, pH 9.0, 45°C

288061

1.5

Metallosphaera sedula

-

65°C

701222

10

Chloroflexus aurantiacus

Q6QQP7

purified recombinant enzyme, pH 7.8, 55°C

725583

200

Metallosphaera sedula

A4YI81

pH 7.4, 65°C, heterologously expressed enzyme

698628

8.7

Bacillus cereus

-

pH 8.5, 37°C

695710

8.8

Bacillus cereus

-

purified recombinant enzyme, pH 8.5, 37°C

695710