1.1.1.276: serine 3-dehydrogenase (NADP+)
This is an abbreviated version!
For detailed information about serine 3-dehydrogenase (NADP+), go to the full flat file.
Reaction
ECTree
1.1.1.276 serine 3-dehydrogenase (NADP+)Advanced search results
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results (Substrates Products
Substrates Products on EC 1.1.1.276 - serine 3-dehydrogenase (NADP+)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-methyl-DL-serine + NADP+
2-amino-2-methyl-3-oxopropanoic acid + NADPH
-
8.7% activity compared to L-serine
-
-
?
2-methyl-DL-serine + NADP+
2-amino-2-methyl-3-oxopropanoic acid + NADPH
-
59% activity compared to L-serine
-
-
?
2-methyl-DL-serine + NADP+
2-amino-2-methyl-3-oxopropanoic acid + NADPH
-
21% activity compared to L-serine
-
-
?
3-hydroxypropanoate + NADP+
3-oxopropanoate + NADPH
-
1.6% activity compared to L-serine
-
-
?
3-hydroxypropanoate + NADP+
3-oxopropanoate + NADPH
-
23% activity compared to L-serine
-
-
?
3-hydroxypropanoate + NADP+
3-oxopropanoate + NADPH
-
13% activity compared to L-serine
-
-
?
D-3-hydroxybutyrate + NADP+
3-oxobutyrate + NADPH
-
1% activity compared to L-serine
-
-
?
D-3-hydroxybutyrate + NADP+
3-oxobutyrate + NADPH
-
12% activity compared to L-serine
-
-
?
D-3-hydroxyisobutyrate + NADP+
2-methyl-3-oxopropanoic acid + NADPH
-
3.5% activity compared to L-serine
-
-
?
D-3-hydroxyisobutyrate + NADP+
2-methyl-3-oxopropanoic acid + NADPH
-
90% activity compared to L-serine
-
-
?
D-3-hydroxyisobutyrate + NADP+
2-methyl-3-oxopropanoic acid + NADPH
-
78% activity compared to L-serine
-
-
?
D-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
55.2% activity compared to L-serine
-
-
?
D-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
83% activity compared to L-serine
-
-
?
D-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
83% activity compared to L-serine
-
-
?
D-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
71% activity compared to L-serine
-
-
?
D-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
71% activity compared to L-serine
-
-
?
D-threonine + NADP+
D-2-amino-3-oxobutanoic acid + NADPH
-
156% activity compared to L-serine
-
-
?
D-threonine + NADP+
D-2-amino-3-oxobutanoic acid + NADPH
-
478% activity compared to L-serine
-
-
?
L-3-hydroxybutyrate + NADP+
3-oxobutyrate + NADPH
-
9% activity compared to L-serine
-
-
?
L-3-hydroxybutyrate + NADP+
3-oxobutyrate + NADPH
-
85% activity compared to L-serine
-
-
?
L-3-hydroxyisobutyrate + NADP+
2-methyl-3-oxopropanoic acid + NADPH
-
8.5% activity compared to L-serine
-
-
?
L-3-hydroxyisobutyrate + NADP+
2-methyl-3-oxopropanoic acid + NADPH
-
96% activity compared to L-serine
-
-
?
L-3-hydroxyisobutyrate + NADP+
2-methyl-3-oxopropanoic acid + NADPH
-
182% activity compared to L-serine
-
-
?
L-allo-threonine + NADP+
L-2-amino-3-ketobutyrate + NADPH
-
best substrate
L-2-amino-3-ketobutyrate spontaneously decarboxylates into aminoacetone
?
L-allo-threonine + NADP+
L-2-amino-3-ketobutyrate + NADPH
-
137% activity compared to L-serine
L-2-amino-3-ketobutyrate spontaneously decarboxylates into aminoacetone
?
L-allo-threonine + NADP+
L-2-amino-3-ketobutyrate + NADPH
-
best substrate
L-2-amino-3-ketobutyrate spontaneously decarboxylates into aminoacetone
?
L-allo-threonine + NADP+
L-2-amino-3-ketobutyrate + NADPH
-
397% activity compared to L-serine
L-2-amino-3-ketobutyrate spontaneously decarboxylates into aminoacetone
?
L-glycerate + NADP+
?
-
5% activity compared to L-serine
-
-
?
L-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
-
-
?
L-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
best substrate
-
-
?
L-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
enzyme belongs to the short-chain alcohol dehydrogenase family, similar reaction mechanism
2-aminomalonate semialdehyde spontaneously decarboxylates into 2-aminoacetaldehyde
?
L-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
-
-
?
L-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
enzyme belongs to the short-chain alcohol dehydrogenase family, similar reaction mechanism
2-aminomalonate semialdehyde spontaneously decarboxylates into 2-aminoacetaldehyde
?
L-serine + NADP+
2-aminomalonate semialdehyde + NADPH
-
-
-
-
?
additional information
?
-
-
no activity with 4-hydroxybutyrate, DL-2-hydroxybutyrate, DL-2-hydroxyisobutyrate, DL-2-hydroxycaproate, DL-2-hydroxyisocaproate, 3-phosphoglycerate, DL-lactate, L-malate, glycollate, glycerol, D-threonine, DL-threo-phenylserine, DL-homoserine, DL-isoserine, L-alanine, beta-alanine, L-aspartate, L-glutamate, L-valine, L-leucine, L-methionine, L-lysine, L-phenylalanine, and glycine
-
-
?
additional information
?
-
-
no activity with DL-homoserine, O-methyl-L-serine, N-acetyl-DL-serine, DL-isoserine, DL-threo-3-phenylserine, malonate, DL-malate, DL-lactate, DL-tartrate, D-gluconate, citrate, isocitrate, glycolate, glycerol
-
-
?
additional information
?
-
-
L-threonine, D-allo-threonine are poor substrates
-
-
?
additional information
?
-
-
no activity with DL-homoserine, O-methyl-L-serine, N-acetyl-DL-serine, DL-isoserine, DL-threo-3-phenylserine, malonate, DL-malate, DL-lactate, DL-tartrate, D-gluconate, citrate, isocitrate, glycolate, glycerol
-
-
?
additional information
?
-
-
L-threonine, D-allo-threonine are poor substrates
-
-
?
additional information
?
-
-
no activity with DL-homoserine, O-methyl-L-serine, N-acetyl-DL-serine, DL-isoserine, DL-threo-3-phenylserine, malonate, DL-malate, DL-lactate, DL-tartrate, D-gluconate, citrate, isocitrate, glycolate, glycerol
-
-
?
additional information
?
-
-
L-threonine, D-allo-threonine are poor substrates
-
-
?
additional information
?
-
-
no activity with DL-homoserine, O-methyl-L-serine, N-acetyl-DL-serine, DL-isoserine, DL-threo-3-phenylserine, malonate, DL-malate, DL-lactate, DL-tartrate, D-gluconate, citrate, isocitrate, glycolate, glycerol
-
-
?
additional information
?
-
-
L-threonine, D-allo-threonine are poor substrates
-
-
?
