1.1.1.272: D-2-hydroxyacid dehydrogenase (NADP+)

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For detailed information about D-2-hydroxyacid dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

(R)-2-hydroxyacid dehydrogenase, (R)-sulfolactate dehydrogenase, (R)-sulfolactate:NAD(P)+ oxidoreductase, 2-D-hydroxyacid dehydrogenase, 2-HDH, 2HADH, D-2-hydroxyacid dehydrogenase, D-isomer specific 2-hydroxyacid dehydrogenase, D2-HDH, DDH, DDH_HALMT, HDH, L-2-hydroxyacid dehydrogenase, L-sulfolactate dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)

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Results	in table
507	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
8	Cofactor
3	Crystallization (Commentary)
18	General Information
13	KM Value [mM]
4	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
13	Organism
8	PDB ID
2	pH Optimum
3	Purification (Commentary)
3	Reaction
3	Reaction Type
12	Reference
1	Renatured (Commentary)
1	Specific Activity [micromol/min/mg]
54	Substrates and Products (Substrate)
4	Subunits
51	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Cloned

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Cloned on EC 1.1.1.272 - D-2-hydroxyacid dehydrogenase (NADP+)

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

expression in Escherichia coli

Haloferax mediterranei

Q2VEQ7

710731

gene ddh, DNA and amino acid sequence determination and analysis, sequence comparison, subcloning and expression in Escherichia coli strains XL1 Blue and BL21(DE3) in inclusion bodies

Haloferax mediterranei

Q2VEQ7

672365

recombinant overexpression of C-terminally His6-tagged enzyme in Escherichia coli

Ketogulonicigenium vulgare

-

742168