1.1.1.236: tropinone reductase II

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For detailed information about tropinone reductase II, go to the full flat file.

Word Map on EC 1.1.1.236

1.1.1.236

tropane

reductases

stramonium

datura

scopolamine

calystegines

solanaceae

hyoscyamine

hyoscyamus

tuberosum

solanum

tuber

solanaceous

alkaloid-producing

n-methylputrescine

3-quinuclidinone

enemies

stereoisomeric

herbivores

n-methyltransferase

nortropane

nonmetal

Reaction

Synonyms

DnTR2, More, pseudotropine forming tropinone reductase, pseudotropine reductase II, pseudotropine-forming tropinone reductase, pseudotropinone forming tropinone reductase, TR-II, TR2, TRII, tropinone (psi-tropine-forming) reductase, tropinone reductase, tropinone reductase I, tropinone reductase II, tropinone reductase-II

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.236 tropinone reductase II

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Results	in table
1	Activating Compound
24	AA Sequence
1	CAS Registry Number
24	Cloned(Commentary)
34	Cofactor
4	Crystallization (Commentary)
1	Expression
11	General Information
5	General Stability
2	Inhibitors
1	kcat/KM [mM/s]
82	KM Value [mM]
21	Molecular Weight [Da]
54	Natural Substrates/ Products (Substrates)
72	Organism
3	Pathway
11	PDB ID
17	pH Optimum
3	pH Range
3	pH Stability
2	pI Value
2	Protein Variants
21	Purification (Commentary)
1	Reaction
3	Reaction Type
71	Reference
85	Source Tissue
8	Specific Activity [micromol/min/mg]
3	Storage Stability
132	Substrates and Products (Substrate)
24	Subunits
39	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Stability [°C]
5	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 1.1.1.236 - tropinone reductase II

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103000

Hyoscyamus niger

major peak, gel filtration

348025

25000 - 55000

Datura stramonium

TRII preparation is not yet pure and shows numerous bands

27500

3 * 27500

27700

3 * 27700, SDS-PAGE

28290

sequence analysis

28310

28400

SDS-PAGE

29000

29420

39000

2 * 39000, SDS-PAGE

69000

minor peak, gel filtration

77700

gel filtration

78500

84000

gel filtration