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1.1.1.225: chlordecone reductase

This is an abbreviated version!
For detailed information about chlordecone reductase, go to the full flat file.

Word Map on EC 1.1.1.225

Reaction

Chlordecone alcohol
+
NADP+
=
Chlordecone
+
NADPH
+
H+

Synonyms

CDR, reductase, chlordecone

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.225 chlordecone reductase

Reference

Reference on EC 1.1.1.225 - chlordecone reductase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Molowa, D.T.; Wrighton, S.A.; Blanke, R.V.; Guzelian, P.S.
Characterization of a unique aldo-keto reductase responsible for the reduction of chlordecone in the liver of the gerbil and man
J. Toxicol. Environ. Health
17
375-384
1986
Oryctolagus cuniculus, Meriones unguiculatus, Homo sapiens, no activity in Cavia porcellus, no activity in Mesocricetus auratus, no activity in Mus musculus, no activity in Rattus norvegicus
Manually annotated by BRENDA team
Winters, C.J.; Molowa, D.T.; Guzelian, P.S.
Isolation and characterization of cloned cDNAs encoding human liver chlordecone reductase
Biochemistry
29
1080-1087
1990
Homo sapiens
Manually annotated by BRENDA team
Molowa, D.T.; Shayne, A.G.; Guzelian, P.S.
Purification and characterization of chlordecone reductase from human liver
J. Biol. Chem.
261
12624-12627
1986
Oryctolagus cuniculus, Meriones unguiculatus, Homo sapiens, no activity in Mesocricetus auratus, no activity in Mus musculus, no activity in Rattus norvegicus
Manually annotated by BRENDA team
Khanna, M.; Qin, I.; Belkin, S.; Sparkes, R.S.; Cheng, K.C.
Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization
Genomics
25
588-590
1995
Homo sapiens
Manually annotated by BRENDA team